Proliferative and non-proliferative retinopathy in patients with diabetes Nutritional, Metabolic, Endocrine
Conditions
Interventions
This is a questionnaire-based observational study planned to be delivered to 220 eligible participants with a diagnosis of diabetic retinopathy and recent Optos widefield fluorescein angiography scans
Sponsors
Moorfields Eye Hospital NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with diabetic retinopathy at various levels have their last available ultrawide field fluorescein angiography done.
Exclusion criteria
Exclusion criteria: 1. Any media opacities that could severely affect the evaluation of retinal non-perfusion on Optos fundus fluorescein angiography. 2. Any condition other than diabetic retinopathy that, from the investigator's point of view, could severely affect the vision.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patients' perceived disease burden, including mobility, self-care, usual activities, pain/discomfort and anxiety/depression, will be measured using the National Eye Institute Visual Functioning Questionnaire (NEI-VFQ 25) and EuroQol Five-Dimensional Questionnaire Five Levels Vision Bolt-on (EQ-5D-5L Bolt-on) at the time around the patient's latest fluorescein angiography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Testing different parameters' ability to reflect a patient's quality of life by comparing each parameter's receiver operating curve (ROC) to diagnose a low NEI-VFQ 25 score cross-sectionally. | — |
Countries
England, United Kingdom
Contacts
Public ContactWei-Shan Tsai
Outcome results
None listed