Clinical comparison between two propofol pumps for general anaesthesia

Schnider versus Eleveld propofol target controller infusion model: a clinical comparison evaluating concentration at the effector site of propofol at loss of responsiveness during anesthesia maintenance and return of responsiveness

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN41934206

Enrollment

Registered

2022-10-25

Start date

2022-10-30

Completion date

Unknown

Last updated

2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anaesthesia Surgery

Interventions

This study will enrol 78 patients who are undergoing breast oncologic surgery. Estimating the mean and standard deviation (SD) from the median and range of the Median Absolute Performance Error (MAPE)

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women undergoing general anesthesia with TIVA-TCI for breast surgery

Exclusion criteria

Exclusion criteria: 1. Patients with any neurologic/respiratory/liver/kidney diseases 2. Patients taking any psychiatric drugs, including benzodiazepines

Design outcomes

Primary

Measure	Time frame
1. Concentration of propofol at loss of consciousness, return of consciousness and during maintenance measured using the display on the equipment 2. Occurrence of deep or light anesthesia during the procedure measured using EEG	—

Secondary

Measure	Time frame
Measured during the procedure measured using EEG: 1. Episodes of deepening anesthesia (BIS 60) 3. Burst suppression 4. Unwanted spontaneous responsiveness	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026