Skip to content

Comparing colonoscopy, sigmoidoscopy and fecal occult blood test for colorectal cancer screening

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN41742401
Enrollment
18000
Registered
2006-07-28
Start date
2002-10-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer, colorectal polyps Cancer Malignant neoplasm of colon

Interventions

Patients, after informed consent, were individually randomized from rosters of GPs or from residents in specific districts or city neighborhoods, either to total colonoscopy or flexible sigmoidoscopy

Sponsors

Italian League Against Cancer (LILT) (Italy)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Men and women aged 55 to 64 who had not been recruited in previous SCORE trials (SCORE and SCORE 2).

Exclusion criteria

Exclusion criteria: 1. Patients unable to give informed consent 2. Patients with terminal illness, inflammatory bowel disease, personal history of polyps or colorectal cancer 3. Patients with two first degree relatives with colorectal cancer 4. Patients who had a colorectal endoscopy or FOBT within the previous two years

Design outcomes

Primary

MeasureTime frame
Attendance and detection rate to total colonoscopy, flexible sigmoidoscopy and FOBT as primary screening tests.

Secondary

MeasureTime frame
Acceptability, complication rates, side effects and costs associated with screening procedures.

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026