A prospective, randomised multicentre study comparing cervical anterior discectomy without fusion, with fusion or with arthroplasty

Conditions

Cervical disk herniation with radiculopathy Musculoskeletal Diseases Cervical disk herniation with radiculopathy

Yang X, Bartels RHMA, Donk R, Arts MP, Goedmakers CMW, Vleggeert-Lankamp CLA.

2019-10-1232 citations

What’s the best surgical treatment for patients with cervical radiculopathy due to single-level degenerative disease? A randomized controlled trial

Roland Donk, André L. M. Verbeek, W. I. M. Verhagen, Hans Groenewoud, Allard J. F. Hosman et al. (6 authors)

PLoS ONE2017-08-2946 citations

10.1371/journal.pone.0183603

An assessment of the most reliable method to estimate the sagittal alignment of the cervical spine: analysis of a prospective cohort of 138 cases

Roland Donk, Michael G. Fehlings, W. I. M. Verhagen, Hisse Arnts, Hans Groenewoud et al. (7 authors)

Journal of Neurosurgery Spine2017-03-0323 citations

10.3171/2016.10.spine16632

Interventions

Anterior surgery without any fusion, with fusion using a cage or arthoplasty

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 55 years 2. Cervical monoradicular symptoms 3. Magnetic resonance imaging (MRI): herniated cervical intervertebral disc and/or osteophyte in accordance with clinical symptoms and signs 4. Involved level not fused

Exclusion criteria

Exclusion criteria: 1. Symptoms and/or signs of myelopathy 2. Previous cervical surgery 3. Psychiatric or mental disease 4. Involvement of liability procedure 5. Alcoholism (drinking more than five units) 6. Insufficient knowledge of the Dutch language 7. Participation in another study 8. Two or more levels involved

Design outcomes

Primary

Measure	Time frame
Clinical outcome after one year estimated by patient self reports: 1. McGill pain questionnaire-Dutch language version (MPQ-DLV) 2. Neck disability 3. 36-item short form questionnaire (SF-36)	—

Secondary

Measure	Time frame
1. Kyphosis on plain x-rays after one and five years 2. MRI at five years to elucidate the quality of the adjacent discs	—

Countries

Netherlands

Outcome results

None listed