Dental caries Digestive System Dental caries
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 4 and 6 years old. 2. Unerupted first permanent molars. 3. No history of any systemic disease. 4. No history of antibiotic use within the recent three months. 5. No use of oral care product containing arginine. 6. No history of periodontal disease. 7. Not any applied fixed or removable retainers.
Exclusion criteria
Exclusion criteria: N/A
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urease and ADS activities are measured using a spectrophotometric assay at baseline, at the end of and 3 months after dental treatment using a spectrophotometric assay. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Dental caries prevalence is evaluated using (dmf(t) at the end of and 3 months after treatment. 2..Oral hygiene is evaluated using the Silness Loe plaque index at the end of and 3 months after treatment. 3. Periodontal health is evaluated using the Loe and Silness gingival index at the end of and 3 months after treatment. 4. Saliva activity is evaluated using unstimulated salivary flow rate at the end of and 3 months after treatment. 5. Saliva activity is evaluated using buffering capacity (BC)) at the end of and 3 months after treatment. | — |
Countries
Turkey