Bipolar Disorder (Type I and II) Mental and Behavioural Disorders Bipolar disorder
Conditions
Interventions
ERP versus TAU
1. A training package for ERP delivered to CCs who are part of Community Mental Health Teams (CMHTs) and who have current active caseloads of people with BD. The training will include
Sponsors
The University of Liverpool (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Lifetime diagnosis of Bipolar Disorder (I or II) 2. Two or more relapses ever and at least one in the last year or two in the last 3 years 3. Currently in contact with healthcare professional attached to a CMHT 4. Working understanding of English language
Exclusion criteria
Exclusion criteria: 1. Substantial cognitive impairment, i.e. moderate/severe learning disability 2. Drug/alcohol abuse/dependence a primary diagnosis, i.e people who use drugs/alcohol are not excluded unless the severity of this would make them unable to engage with the intervention 3. No working understanding of the English language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The effectiveness of the training intervention with CCs assessed by training and CC ratings 2. An estimate of the effect size of the ERP intervention by CCs will be made by comparing patients receiving ERP with those receiving treatment as usual on: a. Time to recurrence to an episode of illness of sufficient severity to reach Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria for major depressive, manic, or mixed episode, based on the Structured Clinical Interview for Depression (SCID) interview b. Assessment of coping using the Coping with Manic and Depressive Prodromes checklist c. The Client Service Receipt Schedule (CSRI) to estimate the use of primary, inpatient, outpatient, day patient, community and emergency services The feasibility will be assessed using quantitative and qualitative data. Quantitative data: 1. Recruitment rates of CMHTs: proportion of teams approached who agreed to take part 2. Attendance rates: the number of training and supervision sessions attended by each care coordinator 3. Care coordinator feedback ratings of training and supervision 4. Service user recruitment rates: number of service users recruited within each group - ERP and TAU 5. Service user retention rates: number of service users that completed follow-up at each point 6. Number of relatives taking part (ERP only) Qualitative data: 1. Interview feedback from care coordinators (ERP and TAU) 2. Feedback from service users and relatives (ERP only) identifying barriers to the intervention. An estimate of the effect size of the intervention will be made using time from baseline to recurrence of an episode of major depression , hypomania, mania, or mixed, satisfying DSM-IV criteria, as the main outcome. All outcomes will be reported allowing for design effect. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Longitudinal analysis of symptom severity using the Longitudinal Interval Follow-up Evaluation (LIFE-II) modified to DSM criteria 2. An estimate of recruitment and drop-out rates 3. Qualitative interviews to gather detailed information from CCs of their experience of training and offering ERP, and from patients with BD and their friends/relatives of their experience of therapy | — |
Countries
United Kingdom
Outcome results
None listed