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A Randomised, Double Blind, Placebo Controlled Study to Assess the Effects of Ranitidine on the Survival of Patients with Gastric Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN41155448
Enrollment
Unknown
Registered
2002-08-19
Start date
2001-01-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Cancer Cancer Gastric

Interventions

1. Arm A: Ranitidine 50 mg in 20 ml 0.9% saline or 5% dextrose to be given intravenously three times daily until oral treatment is tolerated. This will be followed by ranitidine 150 mg tablet twice da

Sponsors

Glaxo Wellcome (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Aged <18 years 2. Gastric cancer proven by histology and endoscopy or barium meal 3. Patients selected for laparotomy must commence intravenous treatment with study drug at the time of induction of anaesthesia 4. Adequate renal function 5. No previous resection for gastric cancer 6. No other prior or concurrent malignancy 7. No treatment with systemic steroids, hormones or other know immunomodulating drugs within the last 7 days prior to the start of the study period 8. No medical contraindications to study treatments

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026