1. Intermediate hyperglycaemia 2. Type II Diabetes Mellitus Nutritional, Metabolic, Endocrine 1. Intermediate hyperglycaemia 2. Type II Diabetes Mellitus
Conditions
Interventions
96 villages are randomly allocated to one of three study arms.
Intervention Arm 1: Community mobilisation through male and female community groups using a Participatory Learning and Action Cycle wher
Sponsors
University College London Institute for Global Health
Eligibility
Sex/Gender
All
Age
30 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Aged 30 years and above 2. Permanent residents in one of the study clusters during the study period
Exclusion criteria
Exclusion criteria: 1. Aged less than 30 years 2. Temporary residents in the study clusters 3. Individuals who decline to participate in the survey
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Combined prevalence of intermediate hyperglycaemia and diabetes among adults aged 30 years or older measured after 18 months of intervention and defined using WHO fasting and two-hour post ingestion of 75g glucose load plasma glucose cut-off categorisations for normoglycaemia, intermediate hyperglycaemia (impaired fasting glucose or impaired glucose tolerance), and type II diabetes mellitus. Blood glucose measures will be recorded from fasting and two-hour post glucose load whole blood samples obtained from finger prick capillaries among a random sample of adults in each of the study clusters using handheld glucometers. 2. Two year cumulative incidence of diabetes among individuals with intermediate hyperglycaemia as defined using WHO diagnostic criteria at baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| The following secondary outcomes will be measured from a random sample of adults aged 30 years or older in each of the study clusters through baseline and endline surveys using trained data collectors: 1. Mean population diastolic and systolic blood pressure derived from the average of two measures or each individual's blood pressure at approximately 5 minute intervals using a digital blood pressure monitor 2. Prevalence of hypertension defined as systolic blood pressure = 140 mmHg or a diastolic blood pressure = 90 mmHg (assessed using digital blood pressure monitor as described above) or self-reported current treatment with antihypertensive medication during the survey questionnaire 3. Mean population body mass index calculated from individual weight and height measures obtained by trained field staff following standard protocols 4. Mean population waist and hip circumference ratio calculated from individual waist and hip measurements obtained by trained field staff following standard protocols 5. Prevalence of overweight and obesity using a cut-off of 23 or more as recommended for South Asian populations 6. Physical activity graded according to the intensity and duration of work (heavy, moderate, mild, and sedentary, based on an equivalent walk of >90 min, 60–90 min, 30–59min, and <30 min/24 h, respectively) based on self-reports in the survey questionnaire 7. Prevalence of inadequate intake of fruit and/or vegetables (< 5 servings/ day), based on self-reports in the survey questionnaire 8. Quality of life measured using the EQ-5D tool in the survey questionnaire 9. Proportion of individuals identified as diabetic by blood glucose testing aware of their diabetic status, based on self-reports in the survey questionnaire 10. Psychological distress among self-reported diabetics measured using the SRQ-20 tool 11. Proportion of population aware of diabetes and able to correctly describe risk factors, symptoms and complications, based on the survey questionnaire 12. | — |
Countries
Bangladesh
Contacts
Public ContactEdward Fottrell
Outcome results
None listed