Is it possible to develop a home based package of interventions delivered by community based women that will improve levels of maternal, newborn, child and HIV care in a disadvantaged community in South Africa?

An effectiveness study of an integrated, community based package for maternal, newborn, child and HIV care in a disadvantaged community in South Africa

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN41046462

Enrollment

3600

Registered

2010-01-04

Start date

2008-06-17

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mother to child transmission of HIV

Interventions

1. Antenatal visit 1 at home Content in this visit will include: 1.1. Antenatal care action ? immunisations/micronutrient supplementation 1.2. Focus on the importance of VCT (linking this with the PMT

further discussion in terms of assisting with the implementation of chosen feeding option 2.6. Additional input on infant communication and the warning signs of postnatal depression 3. Postnatal visi

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: All pregnant women aged 16-49 years who give informed consent for study participation

Exclusion criteria

Exclusion criteria: Does not match inclusion criteria

Design outcomes

Primary

Measure	Time frame
1. HIV free infant survival at 12 weeks postpartum 2. Levels of exclusive and appropriate infant feeding at 12 weeks postpartum	—

Secondary

Measure	Time frame
1. Better uptake of a postnatal clinic visit within 7 days of life 2. Coverage of care and behavioural indicators (antenatal HIV testing, uptake of cotrimoxazole amongst HIV exposed infants at 6 weeks, family planning uptake at 6 weeks) 3. Levels of maternal depression at 12 weeks postpartum 4. To assess whether the intervention is cost-effective compared to improved health facility care alone. This will be evaluated in terms of cost per HIV infection averted and disability-adjusted life years (DALY?s) saved	—

Measure

Time frame

1. Better uptake of a postnatal clinic visit within 7 days of life 2. Coverage of care and behavioural indicators (antenatal HIV testing, uptake of cotrimoxazole amongst HIV exposed infants at 6 weeks, family planning uptake at 6 weeks) 3. Levels of maternal depression at 12 weeks postpartum 4. To assess whether the intervention is cost-effective compared to improved health facility care alone. This will be evaluated in terms of cost per HIV infection averted and disability-adjusted life years (DALY?s) saved

—

Countries

South Africa

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 24, 2026