Topic: Children, Genetics
Conditions
Interventions
Participants will be allocated on a ratio of 1:1 using simple randomisation with permuted blinded block size to:
1. Control group to receive optimised land-based exercises (as defined by local communi
simulated or real functional activities
sub-maximal exercise) (n=20)
Study participants will be assessed for key outcome measures at 3 time points: consent and screen 1 visit
26 week visit. We will collect information on a number of outcomes relating to the feasibility of conducting the trial which will include interviews with participants.
Sponsors
Sheffield Children's Hospital (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Genetically or biopsy confirmed DMD 2. Age 7-16 years 3. Established on glucocorticosteroids 4. North Star Ambulatory Assessment score 8-34 (stable over 4 weeks) 5. Able to complete 10 metre walk (6 minute walk test)
Exclusion criteria
Exclusion criteria: 1.More than a 20% variation between baseline North Star Ambulatory Assessment scores 2.Unable to commit to the programme of twice weekly hydrotherapy for 6 months 3.Any absolute contraindications or precautions to hydrotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The feasibility of recruitment to the main trial | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed