Effect of a dietary fiber and magnesium supplement on endothelial dysfunction, inflammation and glycemic control markers in patients with type 2 diabetes mellitus. Randomized, double-blind clinical trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN40918692

Enrollment

400

Registered

2006-06-30

Start date

2005-11-28

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes mellitus type 2 Nutritional, Metabolic, Endocrine Diabetes

Interventions

There are four arms of treatment. All four groups received the best therapy available to control dm2 which include the ADA nutrition treatment guidelines. There was a nutritionist that gave specific s

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Having diabetes mellitus type 2 (dm2) according to the American Diabetes Association (ADA) criteria 2. Male or female 3. Up to 48 months of dm2 diagnosis 4. Aged 30-70 years

Exclusion criteria

Exclusion criteria: 1. Clinical evidence of chronic complications at the time of enrolment 2. Chronic diarrhea 3. Renal function impairment

Design outcomes

Primary

Measure	Time frame
Biomarkers of endothelial dysfunction (selectin 2, vascular cell adhesion molecules [vcam]) and intercellular adhesion molecule [icam])	—

Secondary

Measure	Time frame
1. Serum levels of inflammation markers (interleukin-6, C-reactive protein) 2. Plasma levels of glycemic control markers (glycated hemoglobin and glucose)	—

Countries

Mexico

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026