Comparing the use of gestational age or weight to estimate Neonatal Endotracheal tube Depth of Insertion (NEDI)

A randomised controlled trial comparing the use of gestational age or weight to estimate Neonatal Endotracheal tube Depth of Insertion (NEDI)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN40879573

Enrollment

Registered

2012-06-12

Start date

2012-01-10

Completion date

Unknown

Last updated

2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal respiratory support Respiratory Neonatal respiratory support

Interventions

Infants in both treatment arms will have an endotracheal tube placed via the mouth Infants randomised to WEIGHT will have the ETT secured at the lips at a depth determined by the form

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Newly born infants [term (> or = 37 weeks' gestation) or preterm (< 37 weeks' gestation)] who are intubated in the neonatal intensive care unit

Exclusion criteria

Exclusion criteria: Infants with known upper airway (e.g. Pierre-Robin sequence) or lung (congenital diaphragmatic hernia) anomalies

Design outcomes

Primary

Measure	Time frame
Endotracheal tube (ETT) tip between the upper border of the 1st thoracic vertebra (T1) and the lower border of the second thoracic vertebra (T2) on chest X-ray	—

Secondary

Measure	Time frame
1. Number of extubations before chest x-ray 2. Repositioning of ETT following chest x-ray 3. Unequal lung expansion on initial chest x-ray following intubation 4. Air leaks - pneumothorax, pneumomediastinum, pulmonary interstitial emphysema 5. Duration of ventilation 6. Oxygen therapy at 28 days 7. Oxygen at 36 weeks 8. Death before discharge from hospital	—

Countries

Ireland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026