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Registry of procalcitonin-guided antibiotic therapy in patients with lower respiratory tract infections outside of study conditions: ?Pro-REAL? - a ?real-life" survey

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN40854211
Enrollment
1200
Registered
2009-10-16
Start date
2009-09-10
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory tract infections Infections and Infestations

Interventions

The participants will be contacted approximately 30 days after the start of the treatment to conduct a telephone interview lasting approximately 10 minutes. They will be asked about any persisting com

Sponsors

BioMérieux (France)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Both males and females, age >18 2. Lower respiratory tract infection (at least one respiratory symptom [cough, sputum production, dyspnea, tachypnea, pleuritic pain]) PLUS 3. One of the following auscultatory finding or sign of infection: 3.1. Core body temperature >38°C or 10 g/L or <4 g/L cells

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

MeasureTime frame
Duration of antibiotic treatment All primary and secondary outcome measures will be assessed by a telephone interview 30 days after the start of the treatment.

Secondary

MeasureTime frame
1. Adherence to procalcitonin algorithm 2. Adverse medical outcomes (complications, mortality, relapse, intensive care unit [ICU] admission) 3. Antibiotic side effects 4. Length of hospital stay 5. Differences between procalcitonin (PCT) levels measured by KRYPTOR® and VIDAS® All primary and secondary outcome measures will be assessed by a telephone interview 30 days after the start of the treatment.

Countries

France, Switzerland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 26, 2026