Periodontal disease and rheumatoid arthritis (RA) Oral Health
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patients diagnosed with active RA and PD from previous cross-sectional descriptive study 1.1. Rheumatoid arthritis was diagnosed according to ACR/EULAR 2010 1.2. The periodontal condition was detected by a periodontist following the criteria of Machtei, 1992
Exclusion criteria
Exclusion criteria: 1. Patients less than 30 years old 2. RAs with other polyarthritides such as polymyalgia, gout, pseudogout, spinal stiffness, Sjögren's syndrome, diabetes mellitus, malignant disease. 3. Less than four real teeth (regardless of the third-largest molars) 4. Received periodontal treatment in the last 3 months 5. Pregnancy, breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Periodontal indicators (plaque index (PlI), gingival index (GI), %BOP (percentage of sites with bleeding on probing), probing pocket depth (PPD), and clinical attachment loss (CAL)) measured at six positions in all teeth at baseline, 3 and 6 months 2. Pain measured using the visual analogue score (VAS) at baseline, 3 and 6 months 3. Pain and swelling of 28 joints assessed using DAS28-CRP activity score at baseline, 3 and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum concentrations of rheumatoid factor (RF) and CRP measured with a latex particle-enhanced method at baseline, 3 and 6 months | — |
Countries
Viet Nam