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Relationship between gum disease and rheumatoid arthritis in Vietnamese patients

Effects of non-surgical periodontal treatment in Vietnamese rheumatoid arthritis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN40789708
Enrollment
82
Registered
2020-06-26
Start date
2012-10-01
Completion date
Unknown
Last updated
2020-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal disease and rheumatoid arthritis (RA) Oral Health

Interventions

Rheumatoid arthritis is diagnosed according to ACR/EULAR 2010 (American College of Rheumatology/ European League Against Rheumatism). The periodontal condition is detected by a periodontist following
details of the sequence were concealed from all clinicians who participated in the study. A staff member not involved in the subsequent experimentation generates a random allocation sequence, in a 1:1

Sponsors

Ho Chi Minh City Medicine and Pharmacy University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adult patients diagnosed with active RA and PD from previous cross-sectional descriptive study 1.1. Rheumatoid arthritis was diagnosed according to ACR/EULAR 2010 1.2. The periodontal condition was detected by a periodontist following the criteria of Machtei, 1992

Exclusion criteria

Exclusion criteria: 1. Patients less than 30 years old 2. RAs with other polyarthritides such as polymyalgia, gout, pseudogout, spinal stiffness, Sjögren's syndrome, diabetes mellitus, malignant disease. 3. Less than four real teeth (regardless of the third-largest molars) 4. Received periodontal treatment in the last 3 months 5. Pregnancy, breastfeeding

Design outcomes

Primary

MeasureTime frame
1. Periodontal indicators (plaque index (PlI), gingival index (GI), %BOP (percentage of sites with bleeding on probing), probing pocket depth (PPD), and clinical attachment loss (CAL)) measured at six positions in all teeth at baseline, 3 and 6 months 2. Pain measured using the visual analogue score (VAS) at baseline, 3 and 6 months 3. Pain and swelling of 28 joints assessed using DAS28-CRP activity score at baseline, 3 and 6 months

Secondary

MeasureTime frame
Serum concentrations of rheumatoid factor (RF) and CRP measured with a latex particle-enhanced method at baseline, 3 and 6 months

Countries

Viet Nam

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026