Topic: Primary Care
Conditions
Interventions
Participants will be randomised to receive either 10mcg vitamin D, 20mcg vitamin D or a placebo
Follow Up Length: 5 month(s)
Sponsors
University of Surrey (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male or female 2. Aged between 14 and 18 years 3. In good health 4. Written informed consent from the adolescent (and parent if required)
Exclusion criteria
Exclusion criteria: 1. Currently receiving treatment for medical conditions likely to affect vitamin D metabolism 2. Hypercalcaemia (>2.5mmol/l) 3. Regular use of sunbeds 4. Having a sun holiday one month prior to commencing the trial or plans for a sun holiday within the study period. 5. Use of vitamin supplements containing vitamin D ? if the prospective participant agrees to stop vitamin D supplementation to join the study, a washout period of 8 weeks prior to commencing the trial would be acceptable. 6. Excessive consumption of alcohol (>14 units per week for females, >21 units per week for males) 7. Smoking >10 cigarettes per day 8. Those following a weight-reducing diet or under dietary restriction (except vegetarianism) 9. Known intolerance/allergy to the constituent ingredients of the daily supplement 10. Clinically significant haematological abnormalities other than mild anaemia (Hb<12.0g/dl) 11. Active malignancy 12. Pregnant or planning a pregnancy during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum 25-hydroxyvitamin D concentrations; Timepoint(s): End of study (20 weeks after supplementation has begun) | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed