Breast cancer Cancer Malignant neoplasm of breast
Conditions
Interventions
The study is non-interventional and laboratory-based. This research is hypothesis-generating rather than a clinical trial.
Biomarker identification, validation and therapeutic targets
Sponsors
University Hospital Southampton (UK)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: All tissue will be obtained from pre-existing sources (tissue bank, archival material surplus to diagnostic requirements, tissue microarrays generated for research purpose). There will be no active patient participation.
Exclusion criteria
Exclusion criteria: All tissue will be obtained from pre-existing sources (tissue bank, archival material surplus to diagnostic requirements, tissue microarrays generated for research purpose). There will be no active patient participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anticipated outcomes from this study are expression levels of candidate biomarkers in breast cancer. The expression levels will be evaluated by various means, but of this study is to determine the optimum methods of biomarker validation. Validate BAG-1 as a bimomarker in breast cancer | — |
Secondary
| Measure | Time frame |
|---|---|
| Identify other proteins related to BAG-1 as possible biomarkers in breast cancer and therapeutic targets | — |
Countries
United Kingdom
Outcome results
None listed