Cataracts Ear, Nose and Throat Cataract, unspecified
Conditions
Interventions
Randomisation of patients:
All patients will undergo routine cataract surgery. At the end of routine surgery the corneal wound will be assessed for an obvious leak. If a leak is found the patient will
Sponsors
Whipps Cross University Hospital (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Fit and well 2. Uncomplicated cataract surgery 3. Male and female patients over 45 years of age
Exclusion criteria
Exclusion criteria: 1. Any patient regarded as having clinically significant blepharitis (contraindication to use of biodendrimer glue) 2. Any patient requiring a general, subtenons or peribulbar anaesthetic 3. Any patient requiring intraoperative trypan blue for capsular visualization 4. Any patient who has an intraoperative complication including capsular rupture, zonular dehiscence, suprachoriodal haemorrhage and vitreous loss 5. Any patient who is found to have an actively leaking wound at the end of surgery 6. Patients aged 45 or younger 7. Patients having undergone previous surgery (i.e., vitrectomy, glaucoma filtration surgery) 6. Patients with pre-existing corneal disease (i.e., keratoconus, Fuch?s endothelial dystrophy) 8. Patients who lack the capacity to consent for cataract surgery (i.e., those who would need a consent form 4 or consultant consent signed for them in their best interests)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Corneal wounds wound be described as gaping internally, gaping externally, open or closed based on morphological characteristics. 2. A log of aqueous trypan blue concentration would be used as a marker for ingress. Measured at 1 hour, 1 day and 1 week post surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient symptoms post-operatively measured at 1 hour, 1 day and 1 week post surgery. | — |
Countries
United Kingdom
Outcome results
None listed