The comparison of pregnancy outcomes in hydrosalpinx patients treated with salpingectomy and proximal tubal occlusion prior to in vitro fertilization embryo transfer

The comparison of pregnancy outcomes in hydrosalpinx patients treated with salpingectomy and proximal tubal occlusion prior to in vitro fertilization embryo transfer: a randomized controlled study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN40458453

Enrollment

100

Registered

2016-12-10

Start date

2017-01-01

Completion date

Unknown

Last updated

2016-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hydrosalpinx Urological and Genital Diseases Chronic salpingitis and oophoritis

Interventions

Participants are randomised to undergo either modified laparoscopic salpingectomy or modified proximal tubal occlusion prior to in vitro fertilization embryo transfer. Prophylactic antibiotics are tr

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Women with tubal infertility planning to undergo IVF 2. 18-41 years old

Exclusion criteria

Exclusion criteria: 1. Endometriosis 2. Prior ovarian surgery 3. Diminished ovarian reserves 4. Polycystic ovarian syndrome (PCOS)

Design outcomes

Primary

Measure	Time frame
1. Clinical pregnancy, defined as gestation sac and/or fetal pole measured using ultrasound scan at 22 days after embryo transfer 2. Ongoing pregnancy, defined as a fetal heartbeat measured on ultrasound beyond 10-weeks gestation	—

Secondary

Measure	Time frame
1. Implantation rate, defined as the number of gestational sacs on ultrasound divided by the number of embryos transferred, measured using ultrasound scan at 22 days after embryo transfer 2. Ectopic pregnancy at any extrauterine site (considered as an implanted embryo), measured using ultrasound scan at 22 days and 35 days after embryo transfer 3. Miscarriage, measured during the first trimester 4. Live birth rate, measured at birth 5. Ovarian reserve, measured using FSH levels on cycle day 2-3 before and 3 months after the laparoscopic surgery	—

Measure

Time frame

1. Implantation rate, defined as the number of gestational sacs on ultrasound divided by the number of embryos transferred, measured using ultrasound scan at 22 days after embryo transfer 2. Ectopic pregnancy at any extrauterine site (considered as an implanted embryo), measured using ultrasound scan at 22 days and 35 days after embryo transfer 3. Miscarriage, measured during the first trimester 4. Live birth rate, measured at birth 5. Ovarian reserve, measured using FSH levels on cycle day 2-3 before and 3 months after the laparoscopic surgery

—

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026