Effect of alfuzosin hydrochloride on female primary bladder neck obstruction

Effect of alpha-1 blocker alfuzosin hydrochloride on female primary bladder neck obstruction

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN40295045

Enrollment

Registered

2008-05-12

Start date

2000-02-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female primary bladder neck obstruction (PBNO) Urological and Genital Diseases Other disorders of bladder

Interventions

Pre-treatment: 1. Urodynamic study including free flow, cystometry, pressure flow study and profilometry, and 2. Bother Score questionnaire Post-treatment: The same as pre-treatment plus a question

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Female patients older than 18 years old 2. Primary bladder neck obstruction

Exclusion criteria

Exclusion criteria: 1. Mechanical causes of obstruction 2. Neurological disorders of micturition 3. Hypotension

Design outcomes

Primary

Measure	Time frame
Urodynamic parameters related with obstruction (voiding phase). Primary and secondary outcomes were measured only at the eight-week visit (study closure).	—

Secondary

Measure	Time frame
1. Measurement of Bother Score Index 2. Global Assessment of Quality of Life 3. Urodynamic parameters related with storage phase Primary and secondary outcomes were measured only at the 8-week visit (study closure).	—

Countries

Greece

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026