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The benefits of early inotropic administration compared to refractory phase inotropic administration in pediatric patients with septic shock

Improvement of serum ferritin levels with inotropic administration in early phase compared to refractory phase in pediatric patients with septic shock: a preliminary randomized controlled trial study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN40192699
Enrollment
13
Registered
2023-01-26
Start date
2019-12-01
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Improvement in the outcome of pediatric patients with septic shock by early administration of inotropic Infections and Infestations

Interventions

Pediatric patients who first came to the paediatric ED in Prof. dr. IGNG Ngoerah Hospital in the study period of December 2019 until December 2020 with a diagnosis of septic shock according to the his

Sponsors

Udayana University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Pediatric patients diagnosed with septic shock and presenting to the pediatric emergency department of RS Prof Ngoerah between December 2019 and December 2020 2. Pediatric patients whose parents agree to sign the informed consent

Exclusion criteria

Exclusion criteria: 1. Pediatric patients with congenital diseases, such as congenital heart disease 2. Undergoing therapy for renal diseases 3. History of prematurity 4. Fluid resuscitation has been done in other healthcare facilities

Design outcomes

Primary

MeasureTime frame
Ferritin levels in blood samples measured using a ferritin test at 1, 6, and 24 hours following the administration of epinephrine

Secondary

MeasureTime frame
Levels in blood samples at 1, 6, and 24 hours following administration of epinephrine: 1. Leukocytes measured using a white blood cell count 2. C-Reactive Protein (CRP) measured using a CRP test 3. Troponin-I measured using a troponin test 4. Lactate measured using a lactic acid test 5. Oxygen saturation measured using a pulse oximeter

Countries

Indonesia

Contacts

Public ContactAnak Agung Lestari Wiradewi
wiradewi@unud.ac.id-

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026