Cervical cancer Cancer Carcinoma in situ of cervix uteri
Conditions
Interventions
A randomised screening study with two groups allocated either to receive an invitation for a routine cervical smear or human papillomavirus (HPV) self-sampling test.
Control group: sen
Sponsors
Queen Mary University of London (UK)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Women aged between 25 - 64 years 2. Eligible for routine cervical screening 3. Have not responded to two invitations to attend for smears
Exclusion criteria
Exclusion criteria: 1. Women who have written to the primary care trust (PCT) to document their refusal to take part in the NHSCSP 2. Women who are not due routine screening as part of the NHSCSP 3. Pregnancy 4. Total abdominal hysterectomy 5. Never been sexually active
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the percentages of women responding to the invitation to return a self-sampling kit versus responding to an invitation for a cervical smear, measured 5 months from the beginning of recruitment. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Response to the invitation for further investigation following a positive test result (colposcopy for women with a smear showing mild dyskaryosis or above, smear +/- colposcopy for those with a positive HPV test), measured 14 months from the beginning of recruitment 2. Response to the request to return a survey regarding demographic information and reasons for previous non-attendance for screening, measured 12 months from the beginning of recruitment | — |
Countries
United Kingdom
Outcome results
None listed