UKOSS: Pandemic COVID-19 in pregnancy

Maternal and perinatal outcomes of pandemic COVID-19 in pregnancy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN40092247

Enrollment

500

Registered

2020-04-01

Start date

2020-03-20

Completion date

Unknown

Last updated

2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 (SARS-CoV-2 infection) in pregnant women Pregnancy and Childbirth

Interventions

Research design: This cohort study will use the UK Obstetric Surveillance System (UKOSS) to identify women hospitalized with pandemic novel coronavirus infection in pregnancy throughout a 6-month peri

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Any pregnant woman hospitalised who has tested positive for COVID-19 will be included. 2. Aged 16-45 years.

Exclusion criteria

Exclusion criteria: 1. Any woman not meeting the criteria.

Design outcomes

Primary

Measure	Time frame
Incidence of pandemic COVID-19 in pregnancy assessed as proportion of pregnant women hospitalised with confirmed COVID-19 disease per 100,000 maternities during the study period	—

Secondary

Measure	Time frame
1. Maternal death assessed using medical records from entry into the study until 6 weeks after giving birth or the end of pregnancy 2. Other major complication (critical care unit admission, receipt of extracorporeal membrane oxygenation [ECMO], confirmed pneumonia on imaging) assessed using medical records from entry into the study until death or hospital discharge 3. Perinatal death assessed using medical records as proportion of babies of pregnant women hospitalised with confirmed COVID-19 who were stillborn at 24 weeks or greater gestation, or who died in the first 7 days of life, per 1000 total births	—

Measure

Time frame

1. Maternal death assessed using medical records from entry into the study until 6 weeks after giving birth or the end of pregnancy 2. Other major complication (critical care unit admission, receipt of extracorporeal membrane oxygenation [ECMO], confirmed pneumonia on imaging) assessed using medical records from entry into the study until death or hospital discharge 3. Perinatal death assessed using medical records as proportion of babies of pregnant women hospitalised with confirmed COVID-19 who were stillborn at 24 weeks or greater gestation, or who died in the first 7 days of life, per 1000 total births

—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 13, 2026