Healthy volunteers Not Applicable
Conditions
Interventions
Participants visited the UC Centre of Clinical Research in four occasions one week apart after 8-12 hours of fasting (only water was allowed). During the first visit, basal biochemical and anthropomet
Sponsors
Pontificia Universidad Católica de Chile
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Female 2. Normoglycemic 3. Normal weight Body Mass Index of 22 ± 1.9 kg/m2 (Mean ± SD)
Exclusion criteria
Exclusion criteria: 1. Family history of diabetes 2. Diabetes 3. Glucose intolerance 4. Dyslipidemia 5. Pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma glucose, insulin levels and c-peptide, measured by blood sample analysis at -15, -5, 15, 30, 60, 90, and 120 minutes after glucose ingestion and meal test. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Glycemic response after meal tests measured by drawing of blood samples at times -15, -5, 15, 30, 60, 90, and 120 minutes after meal test, for the determination of plasma glucose and insulin levels. 2. Anthropometric and biochemical characteristics measured after 8-12 hours of fasting: 2.1 Age (years) 2.2 Weight (kg) 2.3 Height (m) 2.4 BMI (kg/m²) 2.5 Fasting Glucose (mg/dl) 2.6 Fasting Insulin (µIU/ml) 2.7 Total cholesterol (mg/dL) 2.8 HDL cholesterol (mg/dL) 2.9 Triglycerides (mg/dL) 2.10 Systolic arterial pressure (mmHg) 2.11 Diastolic blood pressure (mmHg) The anthropometric measurements were made by personnel trained in light clothing and without shoes, using a calibrated set of stadiometers, scales and tapes. The weight and height were used to calculate the BMI (Kg / m2). Fasting blood samples were taken in the volunteers, and blood glucose, insulinemia, total cholesterol, HDL cholesterol and triglycerides were measured by the laboratory of the Department of Nutrition, Diabetes and Metabolism of the Pontificia Universidad Catolica de Chile | — |
Countries
Chile
Outcome results
None listed