Smoking Cessation Mental and Behavioural Disorders Nicotine addiction
Conditions
Interventions
This is a crossover study in which 7 adults who smoke at least occasionally and who are regular electronic cigarette (EC) users will test at least 4 (and up to 15) different brands of electronic cigar
Sponsors
Queen Mary, University of London (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18 or over 2. Experienced EC users (using EC daily for at least one month) who still smoke conventional cigarettes at least occasionally 3. Willing to attend a series of morning sessions and provide blood samples
Exclusion criteria
Exclusion criteria: 1. Pregnant or breastfeeding 2. Current serious illness 3. Enrolled in other research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PK characteristics of each EC brand. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Comparisons between each brand and conventional cigarette 2. Ranking of brands in Cmax (the highest drug concentration observed in plasma following EC use) 3. Tmax (time at which the highest nicotine concentration occurred in plasma following EC use) 4. AUC (estimated area under the plasma nicotine curve concentration) 5. User ratings | — |
Countries
United Kingdom
Outcome results
None listed