Effects of compression stockings on severity of obstructive sleep apnoea

A randomised controlled trial of the effects of compression stockings on severity and clinical outcomes in obstructive sleep apnoea

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN39411395

Enrollment

Registered

2012-06-21

Start date

2012-06-01

Completion date

Unknown

Last updated

2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnoea Nervous System Diseases Obstructive sleep apnoea

Interventions

Compression stockings prescribed to apply pressure of 20-30 mmHg at the ankle worn during waking hours for two weeks. The control group will not receive any treatment.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Men and women aged 18 to 80 years with OSA (apnoea-hypopnoea index greater than 10)

Exclusion criteria

Exclusion criteria: 1. Venous leg ulcers, history of peripheral vascular disease, heart failure, long-term oxygen therapy, cor pulmonale, major organ transplant, neuromuscular disease, end-stage renal disease on dialysis or adeno-tonsillar hypertrophy 2. Current use of corticosteroids or opiates 3. Treatment for OSA currently or within the last 3 months 4. Current use of compression stockings

Design outcomes

Primary

Measure	Time frame
Apnoea-hypopnoea index measured at baseline and at the end of two weeks	—

Secondary

Measure	Time frame
Changes in: 1. Overnight change in leg and neck fluid volumes (measured by bioimpedance) and neck and calf circumferences 2. Upper airway cross-sectional area, as measured by acoustic pharyngometry 3. Sleepiness, as measured by Epworth sleepiness score 4. Quality of life, as measured by Functional Outcomes of Sleep Questionnaire-10 5. Alertness, as measured by Psychomotor Vigilance Task Measured at baseline and at the end of two weeks	—

Measure

Time frame

Changes in: 1. Overnight change in leg and neck fluid volumes (measured by bioimpedance) and neck and calf circumferences 2. Upper airway cross-sectional area, as measured by acoustic pharyngometry 3. Sleepiness, as measured by Epworth sleepiness score 4. Quality of life, as measured by Functional Outcomes of Sleep Questionnaire-10 5. Alertness, as measured by Psychomotor Vigilance Task Measured at baseline and at the end of two weeks

—

Countries

Canada

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026