Lymphatic drainage of the urinary bladder in bladder cancer patients scheduled for cystectomy

A multimodality technique of single photon emission computed tomography fused with computed tomography (SPECT-CT) and intraoperative verification by gamma probe used to map the primary lymphatic landing sites of the urinary bladder wall in patients scheduled for cystectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN39379749

Enrollment

Registered

2009-02-10

Start date

2007-03-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphatic drainage of urinary bladder in bladder cancer patients Cancer Malignant neoplasm of bladder

Interventions

Preoperative flexible cystoscopy guided injection of technetium into the bladder wall in patients with bladder cancer scheduled for cystectomy and extended PLND. Thereafter, all patients undergo preop

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Both males and females, age range: 18-90 years 2. Invasive urinary bladder cancer 3. Informed consent

Exclusion criteria

Exclusion criteria: 1. T4 bladder cancer 2. Lymph node positive 3. Metastases seen on CT scan 4. Pregnancy 5. Previous operations to the pelvis

Design outcomes

Primary

Measure	Time frame
Lymphatic drainage: regions of the different bladder sites	—

Secondary

Measure	Time frame
Reduction of lymph node dissection field	—

Countries

Switzerland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026