A comparison of two sleep induction drugs used in the intensive care

Etomidate and S-ketamine for endotracheal intubation in the intensive care: a prospective, open study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN39347168

Enrollment

718

Registered

2012-03-30

Start date

2008-04-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endotracheal intubation Surgery

Interventions

Routine procedure, endotracheal intubation. Each patient received one of the following drugs: 1. Etomidate 0.2 - 0.3 mg/kg 2. S-Ketamine 0.5 mg/kg These drugs were used to make the patients sleep bef

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients admitted in the intensive care department

Exclusion criteria

Exclusion criteria: 1. Younger than 18 years 2. Having received etomidate less than 72 hours before

Design outcomes

Primary

Measure	Time frame
Mortality within 28 days	—

Secondary

Measure	Time frame
Cortisol levels	—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026