Low birth weight, preterm labour, hypertension in pregnancy, gestational diabetes Pregnancy and Childbirth Complications of pregnancy, childbirth and the puerperium
Conditions
Interventions
Iintervention group: vaginally 3 g fish oil (1 g DHA) daily for 20 weeks starting until delivery
Control group: vaginally 3 g placebo used as above
Sponsors
Italian Society of Prenatal Diagnosis and Fetal Maternal Medicine (S.I.Di.P.) (Italy)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: All women with a viable foetus between 18+0 and 24+0 weeks of gestation
Exclusion criteria
Exclusion criteria: 1. History of placental abruption 2. Bleeding episode in the present pregnancy 3. Women using (or used) prostaglandin inhibitors 4. Multiple pregnancy 5. Allergy to fish 6. Regular intake of fish oil
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Timing of pregnancy 2. Newborn weight Both endpoints will be measured at the end of the trial. No interim analysis will be performed. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Hypertensive disorders 2. Diabetes Both endpoints will be measured at the end of the trial. No interim analysis will be performed. | — |
Countries
Italy
Outcome results
None listed