Specialty: Anaesthesia, perioperative medicine and pain management, Primary sub-specialty: Anaesthesia, Perioperative Medicine and Pain Management
Conditions
Interventions
Patient Participants: No direct intervention is made as part of the study. Patient anaesthetic records are examined and data on pre-morbid health state and intraoperative blood pressure is collected.
Sponsors
University College London
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged >65 years 2. Underwent general anaesthesia or regional anaesthesia either alone or in combination in an operating theatre 3. Emergency and elective surgery
Exclusion criteria
Exclusion criteria: 1. Procedure requires cardiopulmonary bypass 2. The patient undergoes sedation alone (that is, not in combination with regional anaesthesia)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of elderly patients developing intraoperative hypotension (IOH), the percentage drop from baseline blood pressure and the duration of hypotension. IOH will be recorded from reviewing the patients anaesthetic chart within 24 hours of having surgery. Percentage drop from baseline will be calculated using baselines of pre-induction and pre-operative blood pressure and the lowest recorded value. Duration of IOH will be calculated as the time in minutes spent consecutively at or within 5mmHg of the lowest value recorded on the anaesthetic chart. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. In hospital mortality at 30 days: assessed by review of the clinical record 2. Acute kidney injury within 7 days of surgery: defined as a postoperative creatinine increase =1.5 times the baseline value or =26.5µmol/L. Assessed by review of the clinical record 3. Myocardial injury: Defined as a postoperative troponin enzyme concentration within 7 days of surgery that is above the 99th percentile of the upper reference limit. Assessed by review of the clinical record 4. Stroke, defined as an ischaemic stroke reported from a computed tomography (CT) scan of the brain within 7 days of surgery. Assessed by review of the clinical record 5. Anaesthetist perceptions of and treatment thresholds for hypotension is determined by assessment of a questionnaire administered on the date of participant recruitment | — |
Countries
United Kingdom
Outcome results
None listed