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Musculoskeletal (MSK) Pathways Study

Comparing usual care vs CrossCover Orthopathway clincial decision support system in primary care: a non-inferiority cluster randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN38924614
Enrollment
800
Registered
2023-09-25
Start date
2023-10-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Painful musculoskeletal conditions Musculoskeletal Diseases

Interventions

Orthopathway is a clinician decision support system to be used by clinicians in consultations with patients to reduce variability in care. Orthopathway enables patient-facing clinical staff to follow

Sponsors

Keele University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18 years and over 2. Registered with a participating GP practice during the study period 3. Clinician determined suitability at the point-of-care for trial inclusion 4. Presenting with an MSK problem and a pain intensity score of =4 on a 0 to 10 numerical rating scale at the index consultation

Exclusion criteria

Exclusion criteria: 1. Patients considered vulnerable by their GP (including those on the severe and enduring mental health register, with a diagnosis of dementia, with a recent diagnosis of a terminal illness, who have experienced recent trauma or bereavement, and nearing the end of their life) 2. Patients unable to communicate in English (both in reading and speaking)

Design outcomes

Primary

MeasureTime frame
Musculoskeletal health, as measured by the Musculoskeletal Health Questionnaire (MSK-HQ) at baseline and 3 months

Secondary

MeasureTime frame
1. Clinician confidence in MSK decision-making as measured by a clinician survey at baseline, 6 weeks and 3 months 2. Participant pain intensity as measured by 0-10 visual analogue score (VAS) at baseline, 6 weeks and 3 months 3. Participant quality of life as measured by the EQ5D at baseline, 6 weeks and 3 months 4. Participant experience of consultation and care as measured by Keele Patient Experience Measures at baseline 5. Participant ability to work as measured by modified Work Productivity and Activity Impairment (WPAI) at baseline and 3 months 6. Participant healthcare utilisation measured using self-reported questionnaire data at 3 months, and medical record review data at 3 months 7. Acceptability and experience of Orthopathway explored using qualitative interviews with patient participants and clinicians at 3 months 8. Health economic and carbon reduction analyses using self-reported healthcare utilisation questions and medical record review data at 3 months

Countries

England, United Kingdom

Contacts

Public ContactHollie Birkinshaw
research.mskpathways@keele.ac.uk-

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026