HIV-exposed infants and their mothers Infections and Infestations Human immunodeficiency virus [HIV] disease
Conditions
Interventions
Point-of-care HIV PCR testing is performed on HIV exposed infants around birth in Addington hospital and at Lancers rd primary health care clinic using the Alere™q HIV-1/2 Detect test which is perform
Sponsors
University of KwaZulu-Natal, School of Clinical Medicine, Department of Paediatrics and Child Health
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Infants delivered to HIV infected mothers at Addington hospital 2. Infants presenting for HIV PCR testing at Lancers rd clinic
Exclusion criteria
Exclusion criteria: 1. HIV unexposed infants 2. Infants whose mothers do not give written, informed consent to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity of the point of care testing compared to the standard of care laboratory testing, measured at the time of testing | — |
Secondary
| Measure | Time frame |
|---|---|
| Acceptability of POC testing to mothers and health care workers and operational feasibility of POC testing in both settings, measured using a quantitative/qualitative questionnaire that the mothers are asked at an interview on the day of testing with open and closed ended questions. The staff were interviewed after study completion and a quantitative/qualitative questionnaire with open and closed ended questions is completed at one timepoint. | — |
Countries
South Africa
Contacts
Public ContactElizabeth Spooner
Outcome results
None listed