Skip to content

The effect of probiotics on the absorption of essential nutrients from plant protein

The effect of L. paracasei LP-DG® (CNCM I-1572) and L. paracasei LPC-S01 (DSM 26760) administration on amino acid absorption from plant protein – A placebo-controlled, randomized, double-blind, multicenter, crossover study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN38903788
Enrollment
15
Registered
2020-01-08
Start date
2017-08-01
Completion date
Unknown
Last updated
2020-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy individuals Not Applicable

Interventions

Co-administration of 20 g of protein (vegetable protein isolated from yellow pea (Pisum Sativum), NUTRALYS® S85F, Roquette Freres S.A., France) with either 10 billion CFU of a multi-strain probiotic (

Sponsors

Sofar (Italy)
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Healthy men between the ages of 18–35 years 2. Normal body weight (body mass index (BMI) of 19 – 24.99 kg/m²) 3. Recreationally active (according to American College of Sports Medicine Guidelines) 4. Subjects were not allowed to consume any nutritional or ergogenic supplement known to affect measures of the current study for the prior six weeks, including probiotics, prebiotics and digestive enzymes

Exclusion criteria

Exclusion criteria: 1. Currently being treated for or diagnosed with a gastrointestinal, cardiac, respiratory, circulatory, musculoskeletal, metabolic, immune, autoimmune, psychiatric, hematological, neurological or endocrinological disorder 2. Not weight stable defined as measured body mass deviating by 2% or more 3. Not willing to abstain from alcohol, nicotine, and caffeine for 12 hours prior to each visit

Design outcomes

Primary

MeasureTime frame
Plasma amino acid concentrations measured using tandem-mass spectrometry (LC/MS/MS) at baseline, 30, 60, 120, and 180 minutes post-ingestion

Secondary

MeasureTime frame
Adverse events throughout the study measured using case report forms

Countries

United States of America

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 18, 2026