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The effectiveness of biomaterials filling for protecting exposed dental pulp

The ability of new bioceramic materials used in direct pulp capping in repairing dentine pulp complex: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN38899178
Enrollment
40
Registered
2024-05-01
Start date
2022-06-22
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep carious lesions in asymptomatic permanent teeth Oral Health

Interventions

Forty asymptomatic closed-apex teeth in healthy patients aged between 15-25 years were randomly divided into four groups using http://www.randomization.com: Group A (control): teeth will be treated wi

Sponsors

Damascus University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 25 Years

Inclusion criteria

Inclusion criteria: 1. Teeth with closed apex. 2. No history of trauma. 3. Healthy patients. 4. No radiographic or clinical signs of periapical lesions. 5. Radiographic or clinical symptoms of pulpal necrosis are present. 6. Positive vitality testing (Vital pulp).

Exclusion criteria

Exclusion criteria: 1. Presence of any clinical or radiographic symptoms of acute pulpitis or necrosis. 2. Patients with systematic disease.

Design outcomes

Primary

MeasureTime frame
1. Clinical evaluation: Patients of both groups were recalled after 7 and 30 days of treatment and during radiographical assessment periods (1, 6 and 12 months), where they were asked to rate their pain on the following: 0 No pain. 1 Mild pain. 2 Moderate pain. 3 Severe pain. 2. Radiographical assessment: After coronal restoration was completed a radiograph was taken immediately (R0), After 1 month (R1), After 6 months, and After 12 months (R2). The integrity of the periapical tissue was assessed. Moreover, the following values were given to evaluate the degree of formation of the dentinal bridge radiographically: 0 No dentinal bridge 1 The dentinal bridge begins to form 2 There is complete formation of the dentinal bridge

Secondary

MeasureTime frame
1. Patient age (in years) and sex (male or female) determined during patient examination at the start of treatment 2. Required time for bleeding control of each case (in minutes) measured using a timer.

Countries

Syria

Contacts

Public ContactAlaa Muhamad
alaa3m.muhamad@damascusuniversity.edu.sy+963 933 068 467

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jun 27, 2026