Comparing two routes of administration of progesterone hormone for support in fertilization via intrauterine insemination

Comparison of oral dydrogesterone with vaginal progesterone for luteal phase support in intrauterine insemination

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN38513865

Enrollment

160

Registered

2020-11-04

Start date

2020-09-01

Completion date

Unknown

Last updated

2020-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility Urological and Genital Diseases Female infertility, Assisted fertilization methods, intrauterine insemination, artificial insemination

Interventions

This is a randomized controlled trial, carried out in the reproductive unit in University Malaya Medical Centre and in multicenter hospitals that have sufficient and appropriate expertise and experien

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Infertile women 2. Aged <40 years 3. Undergoing ovarian stimulation with gonadotropins for intrauterine insemination treatment 4. Normal hormonal assay 5. Normal pelvis in transvaginal sonography

Exclusion criteria

Exclusion criteria: 1. Basal levels of FSH =10 mlU/ml 2. Endometriosis stage 3 or 4 3. Severe male factor infertility

Design outcomes

Primary

Measure	Time frame
1. Clinical pregnancy rate outcome measured using serum BHCG at 2 weeks, transvaginal ultrasound scan at 6 weeks, and follow-up appointment trans abdominal ultrasound scan at 12 weeks 2. Miscarriage rate measured using serum BHCG at 2 weeks, transvaginal ultrasound at 6 weeks, and follow-up appointment trans abdominal ultrasound scan at 12 weeks	—

Secondary

Measure	Time frame
1. Patient satisfaction measured using investigator-designed questionnaires at 2 weeks	—

Countries

Malaysia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026