Preimplantation genetic screening Pregnancy and Childbirth Preimplantation genetic screening
Conditions
Interventions
All the patients went through the same (standardised) IVF treatment including ovarian stimulation with hormonal substitution. Follicular aspiration was performed to retrieve oocytes and the male partn
Sponsors
Serono Nordic AB (Sweden)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Couples with infertility of female or male origin 2. Intending to undergo IVF or intracytoplasmic sperm injection (ICSI) 3. Signed a written consent form 4. The age of the woman was over 38 years 5. The couple had to have at least three embryos of good morphological quality (GQE). After an amendment, owing to introduction of SET in Sweden in 2003, only two GQE were required. Randomisation, using a data program, was performed on day three.
Exclusion criteria
Exclusion criteria: Previous enrolment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate, shown as foetal heart activity per randomised patient, measured six to seven weeks after the transfer of the embryo(s). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Pregnancy rate per transfer, measured two weeks after the transfer of the embryo(s) 2. Rate of implantation, measured six to seven weeks after the transfer of the embryo(s) 3. Spontaneous abortion and delivery, measured by looking at hospital records throughout the nine months after the transfer of the embryo(s) | — |
Countries
Sweden
Outcome results
None listed