Cardiovascular: Associated with renal failure Circulatory System Associated with renal failure
Conditions
Interventions
The study has been designed after extensive consultation with our very experienced multidisciplinary renal research team. This will be a randomised, double-blind, placebo-controlled study of the effec
1 teaspoon) to monitor blood potassium levels and should take no longer than 10 minutes. The 3 main visits will each last approximately 2 hours. They will happen right at the beginning, after 4 weeks
Sponsors
Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)
Eligibility
Inclusion criteria
Inclusion criteria: Not provided at time of registration
Exclusion criteria
Exclusion criteria: Not provided at time of registration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Arterial stiffness after 40 weeks of spironolactone/placebo 2. Left ventricular mass, systolic & diastolic dysfunction, heart rate variability, endothelial dysfunction, plasma oxidant and inflammatory markers | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed