PROmotion of Breastfeeding Intervention Trial

Conditions

Healthy, full-term, breastfed infants Pregnancy and Childbirth Breastfeeding

Kramer MS, Davies N, Oken E, Martin RM, Dahhou M, Zhang X, Yang S.

2018-04-018 citations

Effects of Promoting Long-term, Exclusive Breastfeeding on Adolescent Adiposity, Blood Pressure, and Growth Trajectories

Richard M. Martin, Michael S. Kramer, Rita Patel, Sheryl L. Rifas‐Shiman, Jennifer Thompson et al. (11 authors)

JAMA Pediatrics2017-05-0198 citations

10.1001/jamapediatrics.2017.0698

Prospective associations between problematic eating attitudes in midchildhood and the future onset of adolescent obesity and high blood pressure.

Wade KH, Kramer MS, Oken E, Timpson NJ, Skugarevsky O, Patel R, Bogdanovich N, Vilchuck K, Davey Smith G, Thompson J, Martin RM.

2016-12-1421 citations

10.3945/ajcn.116.141697

Effects of Promoting Longer-Term and Exclusive Breastfeeding on Cardiometabolic Risk Factors at Age 11.5 Years

Richard M. Martin, Rita Patel, Michael S. Kramer, Konstantin Vilchuck, Natalia Bogdanovich et al. (13 authors)

Circulation2013-12-0472 citations

10.1161/circulationaha.113.005160

Effects of an intervention to promote breastfeeding on maternal adiposity and blood pressure at 11.5 y postpartum: results from the Promotion of Breastfeeding Intervention Trial, a cluster-randomized controlled trial.

Oken E, Patel R, Guthrie LB, Vilchuck K, Bogdanovich N, Sergeichick N, Palmer TM, Kramer MS, Martin RM.

2013-08-1439 citations

10.3945/ajcn.113.065300

Cohort profile: The promotion of breastfeeding intervention trial (PROBIT).

Patel R, Oken E, Bogdanovich N, Matush L, Sevkovskaya Z, Chalmers B, Hodnett ED, Vilchuck K, Kramer MS, Martin RM.

2013-03-0738 citations

10.1093/ije/dyt003

Effects of promoting longer-term and exclusive breastfeeding on adiposity and insulin-like growth factor-I at age 11.5 years: a randomized trial.

Martin RM, Patel R, Kramer MS, Guthrie L, Vilchuck K, Bogdanovich N, Sergeichick N, Gusina N, Foo Y, Palmer T, Rifas-Shiman SL, Gillman MW, Smith GD, Oken E.

2013-03-01126 citations

10.1001/jama.2013.167

Associations of growth trajectories in infancy and early childhood with later childhood outcomes.

Tilling K, Davies NM, Nicoli E, Ben-Shlomo Y, Kramer MS, Patel R, Oken E, Martin RM.

2011-06-0135 citations

10.3945/ajcn.110.001644

Breastfeeding and child cognitive development: new evidence from a large randomized trial.

Kramer MS, Aboud F, Mironova E, Vanilovich I, Platt RW, Matush L, Igumnov S, Fombonne E, Bogdanovich N, Ducruet T, Collet JP, Chalmers B, Hodnett E, Davidovsky S, Skugarevsky O, Trofimovich O, Kozlova L, Shapiro S, Promotion of Breastfeeding Intervention Trial (PROBIT) Study Group.

2008-05-01600 citations

10.1001/archpsyc.65.5.578

Effect of prolonged and exclusive breast feeding on risk of allergy and asthma: cluster randomised trial.

Kramer MS, Matush L, Vanilovich I, Platt R, Bogdanovich N, Sevkovskaya Z, Dzikovich I, Shishko G, Mazer B, Promotion of Breastfeeding Intervention Trial (PROBIT) Study Group.

2007-09-11160 citations

10.1136/bmj.39304.464016.ae

Interventions

Experimental group: breastfeeding promotion intervention at maternity hospitals and affiliated polyclinics Control group: continuation of maternity hospital and polyclinic practices ex

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Birth weight equal and above 2500 g, either sex 2. Gestational age equal and above 37 weeks 3. Maternal intention to breastfeed

Exclusion criteria

Exclusion criteria: 1. Neonatal disease or condition contraindicating breastfeeding 2. Neonatal disease or condition making breastfeeding difficult or impossible 3. Maternal psychosis 4. Maternal human immunodeficiency virus (HIV) or active tuberculosis (TB) 5. Maternal chemotherapy or radioisotopes

Design outcomes

Primary

Measure	Time frame
One or more episodes of gastrointestinal infection in first 12 months of life.	—

Secondary

Measure	Time frame
Current secondary outcome measures as of 09/01/2013: 1. Respiratory infections in first 12 months 2. Atopic eczema in first 12 months 3. Weight, length, and head circumference at 1, 2, 3, 6, 9, and 12 months 4. Blood pressure (BP) at age 6.5 and 9 years 5. Asthma, hay fever, atopic eczema, and allergy skin tests at age 6.5 years 6. Intelligence quotient (IQ) and behaviour at age 6.5 years 7. Oral/dental health at age 6.5 years 8. Anthropometry, lipoproteins, glucose, insulin, adiponectin, and IGF at age 11 years 9. Maternal height and weight at 6.5 and 11.5 years postpartum 10. Maternal body composition at 11.5 years postpartum 11. Maternal blood pressure at 11.5 years postpartum 12. Child metabolic syndrome at age 11.5 years 13. Eating attitudes at age 11.5 years 14. Child blood pressure at age 6.5, 11.5 and 16 years 15. Child body composition at age 11.5 and 16 years 16. Eczema, asthma, cognition, vision and lung function at age 16 years 17. Length/height and weight throughout childhood Amended as of 11/03/2009: 8. Anthropometry, lipoproteins, glucose, insulin, adiponectin, and IGF at age 11 years Initial information at time of registration: 1. Respiratory infections in first 12 months 2. Atopic eczema in first 12 months 3. Weight, length, and head circumference at 1, 2, 3, 6, 9, and 12 months 4. Blood pressure (BP) at age 6.5 and 9 years 5. Asthma, hay fever, atopic eczema, and allergy skin tests at age 6.5 years 6. Intelligence quotient (IQ) and behaviour at age 6.5 years 7. Oral/dental health at age 6.5 years 8. Lipids,	—

Measure

Time frame

Current secondary outcome measures as of 09/01/2013: 1. Respiratory infections in first 12 months 2. Atopic eczema in first 12 months 3. Weight, length, and head circumference at 1, 2, 3, 6, 9, and 12 months 4. Blood pressure (BP) at age 6.5 and 9 years 5. Asthma, hay fever, atopic eczema, and allergy skin tests at age 6.5 years 6. Intelligence quotient (IQ) and behaviour at age 6.5 years 7. Oral/dental health at age 6.5 years 8. Anthropometry, lipoproteins, glucose, insulin, adiponectin, and IGF at age 11 years 9. Maternal height and weight at 6.5 and 11.5 years postpartum 10. Maternal body composition at 11.5 years postpartum 11. Maternal blood pressure at 11.5 years postpartum 12. Child metabolic syndrome at age 11.5 years 13. Eating attitudes at age 11.5 years 14. Child blood pressure at age 6.5, 11.5 and 16 years 15. Child body composition at age 11.5 and 16 years 16. Eczema, asthma, cognition, vision and lung function at age 16 years 17. Length/height and weight throughout childhood Amended as of 11/03/2009: 8. Anthropometry, lipoproteins, glucose, insulin, adiponectin, and IGF at age 11 years Initial information at time of registration: 1. Respiratory infections in first 12 months 2. Atopic eczema in first 12 months 3. Weight, length, and head circumference at 1, 2, 3, 6, 9, and 12 months 4. Blood pressure (BP) at age 6.5 and 9 years 5. Asthma, hay fever, atopic eczema, and allergy skin tests at age 6.5 years 6. Intelligence quotient (IQ) and behaviour at age 6.5 years 7. Oral/dental health at age 6.5 years 8. Lipids,

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Countries

Belarus

Outcome results

None listed