Skip to content

Automatic versus manual pressure support reduction in the weaning of post-operative patients: a randomised, controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN37456640
Enrollment
80
Registered
2008-07-16
Start date
2002-08-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Weaning from mechanical ventilation Surgery Ventilation

Interventions

To compare two methods of weaning from mechanical ventilation: manual reduction of pressure support (every thirty minutes) versus automatic and computerised method (mandatory rate ventilation) in post

Sponsors

Albert Einstein Hospital (Brazil)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult (more than 18 years old, either sex) mechanically ventilated post-operative ICU patients.

Exclusion criteria

Exclusion criteria: 1. Haemodynamic instability 2. Neurological surgeries 3. Previous pulmonary disease

Design outcomes

Primary

MeasureTime frame
Duration of weaning process. Timepoints: 1. Start of ventilator triggering by the patient 2. Patient extubation

Secondary

MeasureTime frame
1. Levels of pressure support, from the start of spontaneous breathing till extubation 2. Respiratory rate, from the start of spontaneous breathing till extubation 3. Tidal volume, from the start of spontaneous breathing till extubation 4. Respiratory rate/tidal volume (L), from the start of spontaneous breathing till extubation 5. Fraction of inspired oxygen (FIO2), positive end expiratory pressure (PEEP) levels and oxygen saturation during the weaning process, from the start of spontaneous breathing till extubation 6. Need of re-intubation or need of non-invasive ventilation after 48 hours of extubation

Countries

Brazil

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 3, 2026