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Investigating the effects of an eight-week intervention with beetroot on cognitive function and gut health

Investigating the effects of an eight-week intervention with whole beetroot on cognitive function, functional capacity and gut health in older adults

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN37389799
Enrollment
40
Registered
2019-04-03
Start date
2018-01-03
Completion date
Unknown
Last updated
2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive health Digestive System

Interventions

Eight weeks of supplementation with 150g whole cooked beetroot every second day plus one banana OR one banana every second day as a control. Participants were randomised online at ran

Sponsors

Newcastle University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Male or female between the ages of 60 and 80 years 2. In good health i.e. free of chronic illness 3. BMI greater than 20.0kg/m2

Exclusion criteria

Exclusion criteria: 1. Vegetarianism 2. Vitamin or other dietary supplements – will be stopped for 4 weeks previous 3. Active cancer and any diagnosis of malignant cancer in the last 5 years 4. Excessive alcohol intake 5. Allergy or intolerance to the intervention food 6. Smoking 8. Epilepsy 9. Psychoactive medication 10. Mental health issues 11. Repetitive gastric reflux 12. Use of antibiotics in the last month 13. Drugs: corticosteroids, sildenafil, aspirin, anti-hypertensives (Ca2+ channel blockers, ACE inhibitors), diuretics, beta-blockers, antacids, anticoagulants, nitrate-derived agents, and anti-cholinergics. Those on statins and hormone replacement therapy must have had a stable dose over the past 3 months and no changes to dose are to occur during the study

Design outcomes

Primary

MeasureTime frame
Changes in cognitive test scores assessed by CogTrack online cognition programme at baseline, 5 and 9 weeks.

Secondary

MeasureTime frame
1. Functional capacity measured by timed-up-and-go, grip strength and spirometry at baseline, 5 and 9 weeks 2. Gut microbiome measured by bacterial composition and short-chain fatty acid production at baseline, 5 and 9 weeks 3. Blood pressure measured at baseline, 5 and 9 weeks

Countries

United Kingdom

Contacts

Public ContactTess Capper
T.Capper@qub.ac.uk01912088264

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026