Can oxygen delivered into the nose (rather than through a face mask) improve oxygen levels at the start of anesthesia in obese patients undergoing surgery?

Trans-nasal humidified high flow oxygen for preoxygenation in bariatric surgery. A randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN37375068

Enrollment

Registered

2018-10-23

Start date

2018-10-23

Completion date

Unknown

Last updated

2023-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-intubation apnea following anesthesia in obese patients undergoing bariatric surgery Injury, Occupational Diseases, Poisoning

Interventions

Normally in bariatric surgery, the patient is pre-oxygenated during anesthetic induction with 100% oxygen through a face mask until anesthetic induction is completed and the trachea is intubated. Afte

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients undergoing bariatric surgery due to morbid obesity 2. American Society of Anesthesiologists (ASA) Classification I or II 3. Able to understand participant information sheet and give written consent

Exclusion criteria

Exclusion criteria: 1. New York Heart Association (NYHA) Functional Classification >II 2. COPD or asthma causing restrictions in daily activities 3. Restrictive lung disease associated with a reduction of total lung capacity (TLC) of >20% 4. Allergy to any of the anesthetic agents used in the study

Design outcomes

Primary

Measure	Time frame
1. End-tidal oxygen concentration (EtO2) in breath measured at baseline, every 2.5 min until 10 min and after tracheal intubation by the ventilator (Maquet FLOW-i®) 2. Blood gases measured at baseline, every 2.5 minutes until 10 minutes and after tracheal intubation using Abbott's i-STAT®1 portable blood gas analyser. Blood gases are also measured on arrival at the postoperative ward and at 30 and 60 min after arrival.	—

Measure

Time frame

1. End-tidal oxygen concentration (EtO2) in breath measured at baseline, every 2.5 min until 10 min and after tracheal intubation by the ventilator (Maquet FLOW-i®) 2. Blood gases measured at baseline, every 2.5 minutes until 10 minutes and after tracheal intubation using Abbott's i-STAT®1 portable blood gas analyser. Blood gases are also measured on arrival at the postoperative ward and at 30 and 60 min after arrival.

—

Secondary

Measure	Time frame
1. End-tidal carbon dioxide concentration (EtCO2) in breath measured by the ventilator (Maquet FLOW-i®) 2. Peripheral capillary oxygen saturation (SpO2; a measure of haemoglobin oxygenation in blood) measured using the Draeger Infinity® Delta monitor 3. Heart rate measured using the Draeger Infinity® Delta monitor 4. Blood pressure measured using the Draeger Infinity® Delta monitor All secondary outcome measures are measured at baseline, every 2.5 min until 10 min and after tracheal intubation.	—

Measure

Time frame

1. End-tidal carbon dioxide concentration (EtCO2) in breath measured by the ventilator (Maquet FLOW-i®) 2. Peripheral capillary oxygen saturation (SpO2; a measure of haemoglobin oxygenation in blood) measured using the Draeger Infinity® Delta monitor 3. Heart rate measured using the Draeger Infinity® Delta monitor 4. Blood pressure measured using the Draeger Infinity® Delta monitor All secondary outcome measures are measured at baseline, every 2.5 min until 10 min and after tracheal intubation.

—

Countries

Sweden

Contacts

Public ContactDiddi Fors

Diddi.Fors@Akademiska.se+46186111519

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 14, 2026