A trial comparing the effectiveness of Assertive Community Treatment enhanced with evidence based interventions with standard Assertive Community Treatment

The effectiveness of Assertive Community Treatment (ACT) enhanced with evidence based interventions vs. standard ACT: an open randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN37364372

Enrollment

150

Registered

2013-03-15

Start date

2008-07-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severely mentally ill patients with multiple diagnoses: schizophrenia, other non-affective psychoses, affective psychoses, other persistent and severe mental illness, often with comorbid substance abuse, always having led to functional deficits Mental and Behavioural Disorders Mental and behavioural disorders

Interventions

The experimental arm was assertive community treatment with additional evidence based interventions (psycho-education, family interventions, cognitive behavioral therapy and individual placement and s

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adult (male and female) severely mentally ill patients living in the city of Leeuwarden, the Netherlands 2. With an indication for ACT 3. Repeated Health of the Nation Outcome Score (HoNOS) total score of at least 14 before inclusion

Exclusion criteria

Exclusion criteria: Age less than18 years

Design outcomes

Primary

Measure	Time frame
Admission days	—

Secondary

Measure	Time frame
1. Symptom severity, measured by the Positive and Negative Syndrome Scale (PANSS) and the Montgomery Asberg Depression Rating Scale (MADRS) 2. Social functioning (Social Functioning Assessment Scale [SOFAS]) 3. Needs for care (Camberwell Assessment of Needs Short Assessment Scale [CANSAS]) 4. Quality of life (Manchester Short Assessment Scale [MANSA]); the PANSS, MADRS and SOFAS were rated by routIne outcome monitoring nurses during the interview sessions, the CANSAS and MANSA were self-rated by the participants. There were two assessments, the first one closely after inclusion in the trial and the second one two years later.	—

Measure

Time frame

1. Symptom severity, measured by the Positive and Negative Syndrome Scale (PANSS) and the Montgomery Asberg Depression Rating Scale (MADRS) 2. Social functioning (Social Functioning Assessment Scale [SOFAS]) 3. Needs for care (Camberwell Assessment of Needs Short Assessment Scale [CANSAS]) 4. Quality of life (Manchester Short Assessment Scale [MANSA]); the PANSS, MADRS and SOFAS were rated by routIne outcome monitoring nurses during the interview sessions, the CANSAS and MANSA were self-rated by the participants. There were two assessments, the first one closely after inclusion in the trial and the second one two years later.

—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026