Respiratory: Function tests Respiratory Function tests
Conditions
Interventions
Prospective review of pulmonary function tests for patients referred to the pulmonary function laboratory. Participants will be randomised into the order of performing the test. This will either be
Sponsors
Record Provided by the NHSTCT Register - 2007 Update - Department of Health
Eligibility
Inclusion criteria
Inclusion criteria: 25 subjects from each of the following diagnostic groups: a. Healthy volunteers (no lung disease) b. Asthmatics (variable obstructive lung disease) c. COPD (obstructive lung disease) d. Fibrosis (restrictive lung disease) Inclusion criteria: 1. Over 18 years of age 2. Subject must be able to understand and perform lung function test to national guidelines 3. Non or ex-smokers (>6 months) 4. Physician diagnosis of asthma, COPD or lung fibrosis
Exclusion criteria
Exclusion criteria: 1. Haemoptysis of unknown origin 2. Pneumothorax 3. Unstable cardiovascular status (recent MI or PE) 4. Thoracic, abdominal or cerebral aneurysms 5. Recent eye surgery 6. Nausea and vomiting 7. Recent thoracic or abdominal surgical procedures 8. Involved in other studies with licensed drugs or methodology studies within last weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether the timing of subsequent TLco measurements influences the transfer factor measurement. | — |
Secondary
| Measure | Time frame |
|---|---|
| Whether the timing of subsequent TLco measurements influences the alveolar volume measurement. | — |
Countries
United Kingdom
Outcome results
None listed