Chronic kidney disease Urological and Genital Diseases
Conditions
Interventions
This will be a multi-centre, observational, prospective, longitudinal study of approximately 4000 patients to be recruited over two years.
Two core centres in Birmingham (University H
Heart of England Foundation Trust), with a high number of acute admissions and serving a large ethnically diverse population are undertaking this observational study. Additional centres may join to he
Sponsors
University Hospitals Birmingham NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male and female aged 18 years or over 2. Patient from GP practices in the two main Clinical Commissioning Groups served by University Hospital Birmingham NHS Foundation Trust and Heart of England NHS Foundation Trust; i.e. Birmingham South and Central and Birmingham Cross City CCGs
Exclusion criteria
Exclusion criteria: 1. Unable to give informed consent 2. Patient on dialysis or with a working kidney transplant 3. Patient already under long-term follow-up by renal team in secondary care
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Do UK patients classified with chronic kidney disease by their GP have higher hospital re-admission rates than patients not classified with CKD | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Do UK patients classified as having CKD by their GP have higher hospital re-admission rates for a cardiovascular disease event (i.e., hospitalization for acute myocardial infarction, angina, coronary artery bypass graft surgery, percutaneous coronary intervention, peripheral arterial disease, revascularization or stroke) than patients not classified with CKD 2. Do UK patients classified as having CKD by their GP have higher all-cause and cardiovascular mortality than patients not classified with CKD 3. Do UK patients classified as having CKD by their GP receive the same primary and secondary prevention treatments for cardiovascular disease as do patients not classified with CKD 4. Do UK patients classified as having CKD by their GP attain the same targets in the management of chronic diseases as defined by the QOF compared with patients not classified as having CKD 5. Do UK patients classified as having CKD by their GP receive the same treatment for cardiovascular disease when admitted to hospital with a cardiovascular event 6. Do UK patients classified with CKD by their GP derive the same benefit:risk ratio from primary and secondary prevention treatments for cardiovascular disease as do patients not classified with CKD 7. Do UK patients classified with CKD by their GP have a higher risk of further deterioration in renal function (acute kidney injury) than patients not classified with CKD 8. Are there a significant number of patients with biochemical evidence of CKD not classified as such by their GP In addition, there will be a number of secondary analyses performed. All of the above research questions will be analysed separately to investigate the influence of age, ethnicity, SES, deprivation score, gender and concurrent co-morbidities on outcomes, treatment and classifications. | — |
Countries
United Kingdom
Outcome results
None listed