Intermittent claudication
Conditions
Interventions
Supervised exercise therapy versus supervised exercise therapy and PTA.
Sponsors
Imperial College London (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with stable mild to moderate intermittent claudication 2. Patients satisfying the criteria of the Edinburgh Claudication Questionnaire 3. Patients suitable for aorto-iliac or femoro-popliteal PTA after duplex mapping or diagnostic arteriography 4. Ankle Brachial Pressure Indices (ABPI) 0.9 with a positive stress test i.e. a fall of >30 mmHg following a treadmill test at 4 km/h, 10 degree slope for 1 min
Exclusion criteria
Exclusion criteria: 1. Patients with intermittent claudication too mild for patient or doctor to consider PTA 2. Patients with intermittent claudication severe enough to merit consideration of bypass surgery 3. Patients with critical ischaemia i.e. absolute Doppler pressure 50 mmHg 4. Patients with ankle/brachial pressure index (ABPI) >0.9 with a negative stress test who could have sciatica or very mild peripheral arterial disease (insignificant arterial disease) 5. Patients with musculoskeletal, cardiac or any other concomitant disease that renders consideration for supervised exercise inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AWD at 2 years compared to baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Generic and disease specific quality of life questionnaires 2. Cost economics 3. Patency | — |
Countries
United Kingdom
Outcome results
None listed