Urological and Genital Diseases: Peritoneal dialysis Urological and Genital Diseases Peritoneal dialysis
Conditions
Interventions
"Physiological" (pH neutral) versus "standard" (low pH) dialysate solution
Sponsors
Record Provided by the NHSTCT Register - 2007 Update - Department of Health
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients selected to use a PD system that has physiological and standard solutions available
Exclusion criteria
Exclusion criteria: 1. Patients unable to provide informed consent 2. Patients where the use of a certain solution is indicated or contra-indicated for medical reasons (eg known allergy)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patients using physiological solutions will have lower peritonitis rate than control group. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Patients using physiological solutions will have better preservation of residual kidney function 2. Patients using physiological solutions will have smaller changes in peritoneal membrane function assessed by PET than control group 3. Patients using physiological solutions will have reduced composite end-point of mortality and PD failure defined by transfer to HD in patients using physiological solutions | — |
Countries
United Kingdom
Outcome results
None listed