The impact of n-3 fatty acids supplementation on the content of lipids in the pregnant women and the fetus

The impact of EPA and DHA supplementation on the content of lipids in the pregnant women and the fetus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN36705743

Enrollment

Registered

2016-11-09

Start date

2013-06-13

Completion date

Unknown

Last updated

2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy Pregnancy and Childbirth

Interventions

Participants are randomly allocated to one of two groups: 1. Intervention group: Participants take capsules containing 360 mg EPA (eicosapentanoic) and 240 mg DHA (docosahexanoic acid)

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Healthy pregnant women 2. Single pregnancy 2. BMI ( < 25kg/m2) 3. Provision of informed consent

Exclusion criteria

Exclusion criteria: 1. Pregnancy terminated as preterm delivery 2. Pregnant women with chronic illness 3. Pregnant women with gestational diabetes mellitus or preeclampsia

Design outcomes

Primary

Measure	Time frame
1. Concentration of n-3 fatty acids in total serum lipids, measured using gas chromatography at the end of pregnancy/delivery 2. Concentration of n-3 fatty acids in umbilical vein serum, measured using gas chromatography at time of birth 3. Concentration of monounsaturated fatty acids in serum total lipids of umbilical vein serum, measured by gas chromatography at time of birth 4. Concentration of monounsaturated fatty acids in serum total lipids of the mother's serum, measured by gas chromatography at the end of pregnancy	—

Measure

Time frame

1. Concentration of n-3 fatty acids in total serum lipids, measured using gas chromatography at the end of pregnancy/delivery 2. Concentration of n-3 fatty acids in umbilical vein serum, measured using gas chromatography at time of birth 3. Concentration of monounsaturated fatty acids in serum total lipids of umbilical vein serum, measured by gas chromatography at time of birth 4. Concentration of monounsaturated fatty acids in serum total lipids of the mother's serum, measured by gas chromatography at the end of pregnancy

—

Secondary

Measure	Time frame
Weight of mother, measured by weighing scale at recruitment, 20th week of gestation, 30th week of gestation and before delivery	—

Countries

Bosnia and Herzegovina

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 23, 2026