Determining colorectal cancer features using a Rwandan population to lay a foundation and inform precise colorectal cancer clinical management

Molecular and genetic profile of colorectal cancer in Rwanda

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN36459506

Enrollment

300

Registered

2021-12-24

Start date

2019-01-01

Completion date

Unknown

Last updated

2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer Cancer

Interventions

This is a mixed (retrospective and prospective) descriptive laboratory study of colorectal cancer patients who have undergone diagnosis either at King Faisal Hospital (KFH) or at Rwanda Military Hosp

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Histologically confirmed colorectal cancer 2. Diagnosis made or reviewed at King Faisal Hospital (KFH) between 01/01/2019 and 29/02/2021, or prospectively from 21/03/2021 to 31/05/2021 3. Adult

Exclusion criteria

Exclusion criteria: Patients with colorectal masses that are not histologically confirmed

Design outcomes

Primary

Measure	Time frame
MSI status, categorised as MSI-H, MSI-L, or MSS, measured using Promega (MSI Analysis System, Version 1.2) kit at a single time point	—

Secondary

Measure	Time frame
1. Demographics measured from electronic medical records (EMR) at a single time point 2. Family history measured from electronic medical records (EMR) at a single time point 3. Clinical history, including treatment measured from electronic medical records (EMR) at a single time point 4. Diagnostic method (colonoscopy + biopsy) measured from electronic medical records (EMR) at a single time point 5. Location of tumor in the bowel measured from electronic medical records (EMR) and surgery logbooks at a single time point 6. Gross appearance measured from electronic medical records (EMR) at a single time point 7. Histopathological type and grade measured from electronic medical records (EMR) at a single time point 8. Lymphocytic infiltration measured from electronic medical records (EMR) at a single time point 9. Signet-ring cell measured from electronic medical records (EMR) at a single time point 10. Tumor stage measured from electronic medical records (EMR) at a single time point	—

Measure

Time frame

1. Demographics measured from electronic medical records (EMR) at a single time point 2. Family history measured from electronic medical records (EMR) at a single time point 3. Clinical history, including treatment measured from electronic medical records (EMR) at a single time point 4. Diagnostic method (colonoscopy + biopsy) measured from electronic medical records (EMR) at a single time point 5. Location of tumor in the bowel measured from electronic medical records (EMR) and surgery logbooks at a single time point 6. Gross appearance measured from electronic medical records (EMR) at a single time point 7. Histopathological type and grade measured from electronic medical records (EMR) at a single time point 8. Lymphocytic infiltration measured from electronic medical records (EMR) at a single time point 9. Signet-ring cell measured from electronic medical records (EMR) at a single time point 10. Tumor stage measured from electronic medical records (EMR) at a single time point

—

Countries

Rwanda

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026