Low glycemic index diets in type two diabetic subjects treated with oral agents

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN36443696

Enrollment

144

Registered

2004-07-22

Start date

2004-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type two Diabetes Nutritional, Metabolic, Endocrine Diabetes

Interventions

Control: Advice to consume a high cereal fibre, whole grain, normal Glycemic Index (GI) diet (mean GI = 80). Test: Advice to consume a low glycemic index diet (mean GI less than 70) based on differen

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Men and postmenopausal women with type two diabetes, greater than or equal to 18 years old 2. On oral hypoglycemic agents 3. Have fasting plasma HbA1c concentrations between 6.5 and 8.0%

Exclusion criteria

Exclusion criteria: 1. Diabetic complications: clinically significant gastroparesis, retinopathy, nephropathy, neuropathy, hepatic disease or Coronary Heart Disease (CHD) (major coronary event) 2. Major surgery less than six months prior to randomisation, treatment with insulin, acarbose, steroids, or having serum triglycerides more than or equal to 4.0 mmol/L

Design outcomes

Primary

Measure	Time frame
Treatment difference in the change in HbA1c accross treatments.	—

Secondary

Measure	Time frame
1. Fasting blood glucose 2. Fasting insulin 3. High sensitivity C-Reactive Protein (hs-CRP) 4. Oxidized Low Density Lipoprotein (LDL) 5. LDL particle size 6. High Density Lipoprotein (HDL) 7. Change in body weight or oral hypoglycemic agents	—

Countries

Canada

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026