Cardiovascular disease Circulatory System Cardiovascular disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy individuals 2. Male or female 3. Aged 20-50 years
Exclusion criteria
Exclusion criteria: 1. Suffering from any form of known liver disease, diabetes mellitus or a myocardial infarction 2. Suffering from gall bladder problems or abnormalities of fat metabolism 3. On a weight reducing dietary regimen or taking any dietary supplements, including dietary fatty acids 4. Exercising more than three times a week for more than 20 minutes each session 5. Consuming more than 15 units of alcohol per week
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Vasodilation assessed using laser doppler imaging with iontophoresis 2. Vascular measurements were determined within 2 months of the end of the study | — |
Secondary
| Measure | Time frame |
|---|---|
| The antioxidant status was measured by: 1. The ferric reducing antioxidant power (FRAP) assay 2. The oxygen radical absorbance capacity (ORAC) assay 3. By measuring the susceptibility of low density lipoprotein (LDL) to oxidation by a copper catalyst | — |
Countries
United Kingdom