The effect of lifestyle treatment on childhood obesity

A randomised controlled trial evaluating the effect of family-based multidisciplinary cognitive behavioural treatment in children with obesity

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN36146436

Enrollment

Registered

2010-07-13

Start date

2007-03-13

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Childhood obesity Nutritional, Metabolic, Endocrine Obesity

Interventions

The cognitive behaviour treatment program takes two years, with an intensive phase of three monthsat the beginning, followed by booster sessions. In the screening phase the children with their parents

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age 8-17 years (at baseline) 2. Obesity based on BMI values defined by Cole et al. 3. Children/ adolescents presented to the paediatrician 4. Written informed consent from parents and children

Exclusion criteria

Exclusion criteria: 1. Insufficient knowledge/understanding of the Dutch language 2. Children/adolescents following special education 3. Serious co-morbidity 4. Obesity caused by a syndrome (like Prader Willi, Laurence-Moon-Biedl) 5. Endocrine cause of obesity (like hypothyreoidy, Cushing) 6. Obesity caused by medication (like high dose of glucocorticoids) 7. Parents and children/adolescents not willing to invest 40 hours in the treatment 8. Children/adolescents with diabetes mellitus 9. Children/adolescents who already followed a multidisciplinary treatment, including psychological treatment and intensive parent involvement

Design outcomes

Primary

Measure	Time frame
Do children (8-17 yr.) with obesity show a significant decrease (> 0.5 BMI-SDS) in BMI (as defined by Cole et al.[2]) after 3 months of intensive treatment compared to children who were given advice on increased physical activity and dietary changes?	—

Secondary

Measure	Time frame
1. Do children with obesity have a significantly more beneficial effect of 3 months intensive treatment compared to standard care on changes in waist circumference, insulin sensitivity, secretion of gastrointestinal hormones, cardiovascular fitness and quality of life? 2. Will the hypothesized beneficial effects of 3 months intensive treatment in children with obesity persist after 12 and 24 months of follow-up? 3. Are the genetic background of the children, the level of parental education, the social economic status or the ethnicity predictive variables for the degree of obesity in these children, and for the success of treatment?	—

Measure

Time frame

1. Do children with obesity have a significantly more beneficial effect of 3 months intensive treatment compared to standard care on changes in waist circumference, insulin sensitivity, secretion of gastrointestinal hormones, cardiovascular fitness and quality of life? 2. Will the hypothesized beneficial effects of 3 months intensive treatment in children with obesity persist after 12 and 24 months of follow-up? 3. Are the genetic background of the children, the level of parental education, the social economic status or the ethnicity predictive variables for the degree of obesity in these children, and for the success of treatment?

—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 29, 2026